What is the main effect when materials adsorb to the dialyzer membrane?

When materials adsorb to the dialyzer membrane, the primary effect is that they can reduce membrane effectiveness. This occurs because the presence of these materials on the membrane surface can create a barrier that obstructs the passage of waste products and toxins during the dialysis process. When such blockages occur, the efficiency of the dialyzer is compromised, which can impair the removal of solutes from the blood and ultimately hinder the overall efficacy of dialysis treatment.

In hemodialysis, it is essential for the dialyzer to function optimally so that it can adequately filter out impurities. If materials accumulate on the membrane, it can lead to a phenomenon known as fouling, which will not only decrease solute clearance but could also increase the need for higher pressures or longer treatment times to achieve the desired clinical outcomes. This understanding is crucial for healthcare professionals in monitoring and optimizing dialysis sessions for patients.