Patients on digoxin therapy may exhibit what kind of potassium level?

Patients on digoxin therapy may exhibit low potassium levels, a condition known as hypokalemia. Digoxin has a narrow therapeutic index, meaning that the difference between a therapeutic dose and a toxic dose is small. Low potassium levels can enhance the effects of digoxin, increasing the risk of digoxin toxicity, which can lead to serious cardiac complications.

Additionally, hypokalemia can occur due to diuretic therapy, which is often used alongside digoxin in the management of conditions like heart failure or certain arrhythmias. When potassium levels fall, the cardiac muscle cells may be more sensitive to digoxin's effects, exacerbating potential toxicity. Monitoring potassium levels is crucial for patients on digoxin therapy to ensure that they remain within the normal range to avoid both the dangers of hypokalemia and possible digoxin-related complications.